Dr Nicky Mandall BOSF Grant 2000-2003

Juvenile Idiopathic Arthritis (JIA): A screening study to measure class II skeletal pattern, TMJ PDS and use of systemic corticosteroids.

BOSF Grant 2000-2003

Primary investigator

Nicky Mandall

Secondary investigators

E Baildam, R Gray, T V Macfarlane, KD O’Brien , J Davidson, H Foster, J Gardner-Medwin, A Garrahy, CR Mattick D Millett, J Sills, T Walsh, S Ward.


To screen patients with oligoarticular and polyarticular forms of Juvenile Idiopathic Arthritis (JIA) to determine i) the severity of their class II skeletal pattern ii) temporomandibular joint signs and symptoms iii) use of systemic corticosteroids.

Subjects and settings

Sixty eight children with JIA aged between 9-16 years old who were screened at four regional treatment centres in the U.K.


Patients were screened clinically and radiographically for the presence of class II skeletal pattern and temporomandibular pain dysfunction syndrome. In addition, the JIA sub-type and history of disease activity and medication were recorded.


The mean values for class II skeletal pattern were not as severe as expected with an ANB of 4.2 degrees (SD = 2.9 degrees) in the oligoarticular group and 5.1 degrees (SD = 3.8 degrees) in the polyarticular group. Clinical signs and symptoms of temporomandibular joint pain dysfunction syndrome were low (< 20 per cent), except for crepitus and click which affected between 25-40 per cent of JIA children. Radiographically, 57 per cent of oligoarticular and 77 percent of polyarticular cases exhibited condylar erosion. Use of systemic corticosteroids varied between centres, but overall, was prescribed more in polyarticular cases and this is likely to reflect the severity of the disease (P=0.001).


Mandall NA, Gray R, O'Brien KD, Baildam E, Macfarlane TV, Davidson J, Sills J, Foster H, Gardner-Medwin J, Garrahy A, Millett D, Mattick R, Walsh T, Ward S.  Juvenile idiopathic arthritis (JIA): a screening study to measure class II skeletal pattern, TMJ PDS and use of systemic corticosteroids.  J Orthod. 2010 Mar;37(1):6-15.

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